Dermatological Bioactivities of Resveratrol and Nanotechnology Strategies to Boost Its Efficacy—An Updated Review

Resveratrol is a polyphenolic phytoalexin, whose main natural sources are red grapes, wine, berries, and peanuts. When applied to the skin, resveratrol evidences good penetrating capacity low degradation compared oral route, allowing for longer improved topical effect. This bioactive molecule has been gaining interest in dermo-pharmacy cosmetics prevention treatment of skin alterations. Its inherent meritorious biomedical potentials, including anti-aging, photoprotective, estrogen-like, skin-whitening, anti-acne, wound healing, anti-scarring, antimicrobial, anti-skin cancer properties most evident. However, stability hurdles, becoming an unstable when exposed ultraviolet radiation. Several technological strategies have developed improve its stability, efficacy, safety. We described resveratrol, involved mechanisms action, great focus was placed on efficient application dermatological cosmetic formulations, nanotechnology.